Roland Heinig: search on Z-Library

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1

BAY 38–7271: A Novel Highly Selective and Highly Potent Cannabinoid Receptor Agonist for the Treatment of Traumatic Brain Injury

Frank Mauler, Ervin Horváth, Jean De Vry, Rainer Jäger, Thomas Schwarz, Steffen Sandmann, Corinna Weinz, Roland Heinig, Michael Böttcher

Journal:

CNS Drug Reviews

Year:

2003

Language:

english

File:

PDF, 152 KB

english, 2003

2

Pharmacokinetics, safety and tolerability of the novel, selective mineralocorticoid receptor antagonist finerenone - results from first-in-man and relative bioavailability studies

Lentini, Silvia, Heinig, Roland, Kimmeskamp-Kirschbaum, Nina, Wensing, Georg

Journal:

Fundamental & Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.40 MB

english, 2016

3

Pharmacokinetics of the Novel, Selective, Non-steroidal Mineralocorticoid Receptor Antagonist Finerenone in Healthy Volunteers: Results from an Absolute Bioavailability Study and Drug–Drug Interaction Studies In Vitro and In Vivo

Heinig, Roland, Gerisch, Michael, Engelen, Anna, Nagelschmitz, Johannes, Loewen, Stephanie

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2018

Language:

english

File:

PDF, 659 KB

english, 2018

4

Pharmacokinetics of Metrifonate and its Metabolite Dichlorvos in Healthy Volunteers and in Patients with Renal Impairment

Roland Heinig, Hartmut Dietrich, Atef Halabi

Journal:

Clinical Drug Investigation

Year:

1999

Language:

english

File:

PDF, 205 KB

english, 1999

5

Pharmacokinetics of the Novel Non-Steroidal Mineralocorticoid Receptor Antagonist Finerenone (BAY 94-8862) in Individuals with Renal Impairment

Heinig, Roland, Kimmeskamp-Kirschbaum, Nina, Halabi, Atef, Lentini, Silvia

Journal:

Clinical Pharmacology in Drug Development

Year:

2016

Language:

english

File:

PDF, 891 KB

english, 2016

6

The Pharmacological Basis for Metrifonate’s Favourable Tolerability in the Treatment of Alzheimer’s Disease

Schmidt, Bernard H., Heinig, Roland

Journal:

Dementia and Geriatric Cognitive Disorders

Year:

1998

Language:

english

File:

PDF, 220 KB

english, 1998

7

Biotransformation of Finerenone, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, in Dogs, Rats, and Humans, In Vivo and In Vitro

Gerisch, Michael, Heinig, Roland, Engelen, Anna, Lang, Dieter, Kolkhof, Peter, Radtke, Martin, Platzek, Johannes, Lovis, Kai, Rohde, Gabriele, Schwarz, Thomas

Journal:

Drug Metabolism and Disposition

Year:

2018

Language:

english

File:

PDF, 702 KB

english, 2018

8

Development, validation and application of assays to quantify metrifonate and 2,2-dichlorovinyl dimethylphosphate in human body fluids

Roland Heinig, Dieter Zimmer, Shirley Yeh, George J Krol

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

9

Single dose pharmacokinetics, pharmacodynamics, tolerability and safety of BAY 60–5521, a potent inhibitor of cholesteryl ester transfer protein

Michael-Friedrich Boettcher, Roland Heinig, Carsten Schmeck, Christian Kohlsdorfer, Matthias Ludwig, Anja Schaefer, Sabine Gelfert-Peukert, Georg Wensing, Olaf Weber

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 4.25 MB

english, 2012

10

Pharmacokinetics of Escalating Doses of Intravenous Repinotan in Healthy Male Volunteers

Dr Roland Heinig, Michael F. Böttcher

Journal:

Clinical Drug Investigation

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

11

Effect of Gender and Age on the Pharmacokinetics of Repinotan

Dr Roland Heinig, Pavur Sundaresan, Anita Shah, Michael Boettcher

Journal:

Clinical Drug Investigation

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

12

Pharmacokinetics of the Novel Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone (BAY 94-8862) in Individuals with Mild or Moderate Hepatic Impairment

Heinig, Roland, Lambelet, Marc, Nagelschmitz, Johannes, Alatrach, Abir, Halabi, Atef

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2019

Language:

english

File:

PDF, 680 KB

english, 2019

13

Population Pharmacokinetic and Exposure–Response Analysis of Finerenone: Insights Based on Phase IIb Data and Simulations to Support Dose Selection for Pivotal Trials in Type 2 Diabetes with Chronic Kidney Disease

Snelder, Nelleke, Heinig, Roland, Drenth, Henk-Jan, Joseph, Amer, Kolkhof, Peter, Lippert, Jörg, Garmann, Dirk, Ploeger, Bart, Eissing, Thomas

Journal:

Clinical Pharmacokinetics

Year:

2019

Language:

english

File:

PDF, 1.17 MB

english, 2019

14

Disposition of a Single Dose of Warfarin in Healthy Individuals after Pretreatment with Metrifonate

Dr Roland Heinig, Nicholas Kitchin, Paul Rolan

Journal:

Clinical Drug Investigation

Year:

1999

Language:

english

File:

PDF, 203 KB

english, 1999

15

Prediction of a potentially effective dose in humans for BAY 60–5521, a potent inhibitor of cholesteryl ester transfer protein (CETP) by allometric species scaling and combined pharmacodynamic and physiologically-based pharmacokinetic modelling

Olaf Weber, Stefan Willmann, Hilmar Bischoff, Volkhart Li, Alexandros Vakalopoulos, Klemens Lustig, Frank-Thorsten Hafner, Roland Heinig, Carsten Schmeck, Klaus Buehner

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 4.07 MB

english, 2012

16

Pupil Reaction: A Valid Sensitive Clinical Biomarker for 5-HT1A Compounds

Michael Boettcher, Roland Heinig, Georg Wensing, Jochen Kuhlmann

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2005

Language:

english

File:

PDF, 39 KB

english, 2005

17

Evaluation of Interethnic Differences in Repinotan Pharmacokinetics by Using Population Approach

Tanigawa, Takahiko, Heinig, Roland, Kuroki, Yoshihiro, Higuchi, Shun

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2006

Language:

english

File:

PDF, 254 KB

english, 2006

18

[IEEE 2013 19th International Workshop on Thermal Investigations of ICs and Systems (THERMINIC) - Berlin, Germany (2013.09.25-2013.09.27)] 19th International Workshop on Thermal Investigations of ICs and Systems (THERMINIC) - Electro-thermal co-design of chip-package-board systems

Sohrmann, Christoph, Heinig, Andy, Dittrich, Michael, Jancke, Roland, Schneider, Peter

Year:

2013

Language:

english

File:

PDF, 2.13 MB

english, 2013

19

Proposal for defining the relevance of drug accumulation derived from single dose study data for modified release dosage forms

Scheerans, Christian, Heinig, Roland, Mueck, Wolfgang

Journal:

Biopharmaceutics & Drug Disposition

Year:

2015

Language:

english

File:

PDF, 227 KB

english, 2015

20

Population Pharmacokinetic and Exposure–Response Analysis of Finerenone: Insights Based on Phase IIb Data and Simulations to Support Dose Selection for Pivotal Trials in Type 2 Diabetes with Chronic Kidney Disease

Snelder, Nelleke, Heinig, Roland, Drenth, Henk-Jan, Joseph, Amer, Kolkhof, Peter, Lippert, Jörg, Garmann, Dirk, Ploeger, Bart, Eissing, Thomas

Journal:

Clinical Pharmacokinetics

Year:

2019

File:

PDF, 1.17 MB

2019

21

Clinical Pharmacokinetics of Nisoldipine Coat-Core

Dr Roland Heinig

Journal:

Clinical Pharmacokinetics

Year:

1998

Language:

english

File:

PDF, 214 KB

english, 1998

22

Pharmacokinetics of a New Orodispersible Tablet Formulation of Vardenafil

Dr Roland Heinig, Boris Weimann, Hartmut Dietrich, Michael-Friedrich Böttcher

Journal:

Clinical Drug Investigation

Year:

2011

Language:

english

File:

PDF, 210 KB

english, 2011

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